Cytokine (dimeric, subunits 50 kD) very similar to PD-ECGF. Neurotrophic for cortical neurons and inhibits proliferation of astrocytes (stimulates differentiation). May play a part in aberrant neovascularisation of rheumatoid synovium.

Dictionary of molecular biology. 2004.

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  • ECGF1 — Endothelial cell growth factor 1 (platelet derived), also known as ECGF1, is a human gene. PBB Summary section title = summary text = Platelet derived endothelial cell growth factor (ECGF1) is an angiogenic factor which promotes angiogenesis in… …   Wikipedia

  • PD-ECGF — (= platelet derived endothelial cell growth factor) Cytokine (471 residues) produced by platelets, fibroblasts and smooth muscle cells. Stimulates endothelial proliferation in vitro and angiogenesis in vivo. Also promotes survival and… …   Dictionary of molecular biology

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